故事发生在波士顿，讲述绝望的父亲被迫联手一名惯犯，洗劫腐败的政客，在劫案出了岔子之后，二人在一位心理治疗师的帮助下，寻找活命的出路。

蜜桃女敏子（小日向しえ饰）是一个在乡下旅馆打工的平凡女孩，她终日活在变态叔父曽根崎道夫（島田洋八饰）的阴影之下，心中苦闷不堪。某日，敏子选择出逃，希望展开新的生活，然而却在半路遭遇一伙两年前曾打劫她所在旅馆的劫匪。劫匪之一鲨皮男（浅野忠信饰）背叛老大田拔政二（岸部一徳饰），私吞组织一亿日元绝路逃亡。他和敏子宛如极道鸳鸯，携手朝着各自的新生活狂奔而去。而曾根崎和田拔一伙则紧随其后。奇妙的追逐由此展开，一切开始朝着不可预测的方向发展……本片根据望月峰太郎的同名漫画原作改编，为广告导演石井克人的电影导演处女作。

老牌喜剧明星威尔·法瑞尔和约翰·C·赖利将再次联手，加盟索尼喜剧新片《福尔摩斯与华生》。法瑞尔和赖利分饰大侦探福尔摩斯与福尔摩斯的助手华生。 　　法瑞尔主演的《狱前教育》导演伊坦·柯亨，他将担任《福尔摩斯&华生》的导演。该片剧本受阿瑟·柯南·道尔的福尔摩斯系列小说启发，是一部PG-13的喜剧。索尼最初买下剧本时，本来想让法瑞尔和萨莎·拜伦·科恩（《塔拉迪加之夜：瑞奇鲍比的民谣》）主演，但后来没了下文。 　　索尼计划今年感恩节（11月24日）后马上开拍。预计在明年可以上映。

比尔很是反感其父母整日出入于阶级社会打交道，自从他的朋友理查德死于车祸后，其家人的行为越来越奇怪，比尔决定暗中调查他们，结果却发现一个惊天秘密 （这部精彩的电影是活魔人原班人马制作，1990年布鲁塞尔奇幻电影节最佳化妆特效奖得主， 片子对当代社会的讽刺可谓是 前无古人后无来者，赤裸裸地揭露了资本主义的邪恶本质，乃当今恐怖迷必看影片之一）

　　UCLA college student Jonathan Moore (Anthony Edwards) is playing a game called "Gotcha" (popular on mid-1980s college campuses as "Assassin" or "Tag"), wherein the players are all assigned a mock "hit" on another player by use of a harmless paintball gun. Moore and his apartment roommate Manolo go on a vacation to Paris, France. After touring some of Paris, in a cafe Moore meets Sasha Banicek (Linda Fiorentino), a Czechoslovakian girl. Eventually, Jonathan has intercourse with Sasha, losing his virginity.
　　Jonathan decides to leave Manolo (who is heading to Spain) and go with Sasha to West Berlin to spend more time with her. Jonathan believes that he is in love with Sasha. There, Jonathan and Sasha continue to have sex and even go to an Oktoberfest beer gathering. One night, Sasha tells Jonathan that she has to go to East Berlin to pick up a package. One night after arriving in East Berlin, Sasha leaves their hotel room and walks to dark street corner. There, Sasha meets a German man who tells her the location of the pickup of her package. Meanwhile, Sasha was being monitored by a Soviet agent, who was sitting in a car at a distance. During the day, Sasha tells Jonathan that if she gives him a certain message, it means that he has to leave East Berlin immediately. At a cafe, Sasha gives Jonathan a package and says that a strudel is inside. A little later, Sasha tells Jonathan to meet her at the butcher shop near their hotel. All of a sudden, a Soviet agent begins to chase after Sasha. Sasha decides to use Jonathan (who is holding her package) to unknowingly get the package over to West Berlin. Meanwhile, Sasha is taken by the Soviet agent and East German secret police.
　　Jonathan goes to Checkpoint Charlie to cross the heavily fortified border into West Berlin. At the East German customs search, Jonathan is stripped of his clothes and given a cavity search. Meanwhile, Sasha is stripped and searched for possible espionage evidence. Vlad arrives at the border crossing to search for Jonathan, however Jonathan passes the border safely before he can be captured. Once in West Berlin, Jonathan feels liberated by the Westernized society. In the hotel, Jonathan receives a message from Sasha to meet him at a specified location. Jonathan finds out that his hotel room was broken into and robbed of his traveler's checks. Soviet agents eventually find Jonathan in West Berlin and chase him throughout a public park. Jonathan jumps into a water canal and manages to escape from the Soviets and stumbles upon a German rock group headed for Hamburg, who offer him a ride to the airport.
　　The rock group successfully get Jonathan to the airport (using full-face makeup to sneak him past a checkpoint) and Jonathan finally arrives in Los Angeles Tom Bradley International Airport and to his apartment. Soon, Vlad and a band of Soviet agents arrive too in Los Angeles. Once home, Jonathan stumbles upon a film canister, which was planted by Sasha. Jonathan visits his parents and tells them what happened in Germany but they cannot believe a word of it and think Jonathan is on drugs. Jonathan decides to call the FBI then the Central Intelligence Agency for help. Jonathan returns to find his apartment broken into and looted.
　　The CIA officer tells Jonathan to give them the photo film canister. At the Los Angeles headquarters of the CIA, Jonathan spots Sasha who looks like she was working there. Jonathan eventually meets up with Sasha. Sasha admits that she is Cheryl Brewster, a CIA agent, originally from Pittsburgh. Out of nowhere, Vlad and his gang begin to chase Jonathan and Cheryl on the UCLA campus. Jonathan eliminates all the Soviets with a tranquilizer gun which he gets from the campus veterinary sciences building. The Soviets are arrested, the CIA agents thank Jonathan for his (indirect) help in obtaining the film, and Sasha tells him she wants to continue their relationship.
　　After they part, Jonathan talks to a pretty student who rebuffs him coldly. As she walks away, he aims the tranquilizer pistol and shoots her in the rear.

　　大卫.尼文遗作，彼得.塞勒斯已逝，该续集以一个替代品主角去寻找失踪的前主角克鲁索穿针引线，导演致敬了过去的几部粉红豹电影(克鲁索博物馆、大卫尼文和卡普西尼)、倒唱的《月亮河》、《狂欢宴》的酒鬼等。最抢眼的是罗杰.摩尔客串被整容的克鲁索。电脑选人那段后来被港片《最佳拍档》借去。

艾迪（乔什·布洛林JoshBrolin饰）是一名效力于国会制片厂的制片人，表面看来，这是一份光鲜亮丽的职业，艾迪整天出入于高端场所和宴会之中，打交道的都是大明星和各路社会名流，可实际上，艾迪真正在干的，是帮这群整天闲着没事干尽惹麻烦的巨婴们“擦屁股”的活计。导演劳伦斯（拉尔夫·费因斯RalphFiennes饰）不小心让知名女明星狄安娜（斯嘉丽·约翰逊ScarlettJohansson饰）怀孕了，艾迪必须想办法让这件事成为永远的秘密。酗酒成性的老演员拜尔德（乔治·克鲁尼GeorgeClooney饰）在新片即将开机之前竟然遭人绑架，筹得10万美元赎金的活也落在了艾迪的头上，除此之外，艾迪还要谨防对明星八卦虎视眈眈的双胞胎娱记赛克姐妹（蒂尔达·斯文顿TildaSwinton饰）。

　　劳伦和桑迪都生长在纽约，这两个年轻女演员的出身和性格似乎都处于不可调和的两个极端：优雅迷人的劳伦一心盼望着能扮演哈姆雷特，而粗俗矮胖的桑迪则对哈姆雷特一无所知。她们在同一个班学习表演时都倾心于英俊的教师迈克尔·桑切斯。但有一天，桑切斯却突然失踪了。劳伦和桑迪这对冤家一起去找他，但在寻找的过程中两人都发现了对方身上的优点，遂结为了好友。她们看见桑切斯进了一家花店，随后花店发生了爆炸。警察说桑切斯被炸死了，但她们又看到了桑切斯，还跟踪他到了湖边的小屋里。中央情报局的特工告诉了她们一个惊人的消息：原来桑切斯是苏联的克格勃，他逼迫美国政府用重金赎回他偷走的装有化学毒品的瓶子。桑切斯在她们准备帮助政府将瓶子偷回时将劳伦拐走，劳伦趁其不备时逃了出来，在追逐的过程中，桑切斯失足摔死。风波过去后，劳伦和桑迪回到了纽约。劳伦的心愿终于得到了满足，她扮演了梦寐以求的哈姆雷特，而桑迪扮演的则是哈姆雷特的情人奥菲莉娅。

Phoebe and fellow American Julian Peters meet in Rome, find a lost dog, and agree to return it to Monte Carlo to split the five thousand dollar reward. Discovering the dog's owner dead, they panic and become fugitives. Other victims of misfortune also become suspects, as the plot twists and luck and judgment desert everyone.