WhenanencounterwiththeswingingscenehasanunexpectedimpactonDavid'simpotence,Alicethinksshemighthavefoundthesolutiontoalltheirproblems,butthepoly-amorousworldisadifficultplaceforalovestorytoflourish.

英国男孩保罗从向来忽视他的家庭出走，老天却安排了他与一个生活在相似家庭环境下的法国女孩米谢勒成为了朋友。他们在法国罗讷河三角洲的一个美丽的地中海海滨小城卡梅格象一对恋人一样组成了一个家庭，过着田园诗般的生活，后来还生了孩子，并担负起成年人的责任……

　　尼加拉瓜大瀑布，一段离奇惊险的蜜月之旅。刚结婚不久的新郎赛拉斯·帕克（詹姆斯·弗兰科 James Franco饰）与新娘卡蜜儿·福斯特（西耶娜·米勒 Sienna Miller饰）踏上了这次危情冒险之旅。脾气阴晴不定的赛拉斯是个刚刚被假释的小偷，而活泼单纯的卡蜜儿正是他保释官的侄女。赛拉斯一心只想利用这次蜜月之旅逃往加拿大，卡蜜儿则坚信这次尼加拉瓜瀑布之旅，能够彻底改变赛拉斯。
　　然而一场突如其来的车祸，瞬间夺去了卡蜜儿的生命。当赛拉斯前去报警时，却惊奇的发现卡蜜儿起死回生。随后更发生了一连串不可思议的离奇事件。

　　The moon rises at a predestined angle and awakens the sleeping Dr. Phibes in 1928, three years after the events of the previous movie. To his dismay, he finds that his house has been demolished and his papyrus scrolls stolen, the scrolls he needs to find the Pharaoh's Tomb in Egypt, where the River of Life flows. After identifying the source of the papyrus theft, he packs and leaves for Egypt with his assistant Vulnavia - whose face displays no effects from the acid shower she received at the end of the previous film (although the character is now played by a different actress, Valli Kemp). His primary goal is the awakening of his dead wife, Victoria.
　　The thieves of Phibes' scrolls suffer an attrition problem as Inspectors Trout and Waverly chase Phibes across the world. The party is led by Beiderbeck (Robert Quarry, best known for playing Count Yorga). Although he looks young, he is several hundred years old and wants to find the River of Life in order to stay alive and be with his lover Diana (Fiona Lewis) forever. This time Phibes' murders all have an Egyptian theme to them; for example, one character is sand-blasted to death. Other deaths include someone being stung to death by scorpions, being eaten by an eagle (in the original script impaled by a gold eagle in the same way a doctor in The Abominable Dr. Phibes was impaled by a golden unicorn), and a golden snake piercing someone's skull.
　　At the climax, Beiderbeck sacrifices his life in order to save Diana. The film ends with Phibes riding a raft down the River of Life with Victoria, while singing "Over the Rainbow" (which is strange, as this film is set in 1928 but "Over The Rainbow" wasn't written until 1938). It is left ambiguous whether Victoria is resurrected or not, although a picture inside the DVD shows her in the raft with her eyes open and smiling at the camera